Roy L Silverstein Selected Research

Scavenger Receptors (Scavenger Receptor)

1/2020	Cysteine sulfenylation by CD36 signaling promotes arterial thrombosis in dyslipidemia.
1/2019	CD36 signaling in vascular redox stress.
1/2018	Oxidized Lipid Uptake by Scavenger Receptor CD36 (Cluster of Differentiation 36) Modulates Endothelial Surface Properties and May Contribute to Atherogenesis.
7/2014	Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression.
10/2011	Vav protein guanine nucleotide exchange factor regulates CD36 protein-mediated macrophage foam cell formation via calcium and dynamin-dependent processes.
3/2011	Vav family Rho guanine nucleotide exchange factors regulate CD36-mediated macrophage foam cell formation.
2/2011	A CD36-dependent pathway enhances macrophage and adipose tissue inflammation and impairs insulin signalling.
1/2010	Mechanisms of cell signaling by the scavenger receptor CD36: implications in atherosclerosis and thrombosis.
12/2009	Type 2 scavenger receptor CD36 in platelet activation: the role of hyperlipemia and oxidative stress.
12/2009	Lipid-induced insulin resistance is associated with increased monocyte expression of scavenger receptor CD36 and internalization of oxidized LDL.

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Roy L Silverstein Research Topics

Disease

20	Atherosclerosis 01/2022 - 10/2002
16	Thrombosis (Thrombus) 01/2020 - 06/2008
11	Neoplasms (Cancer) 01/2021 - 02/2003
9	Inflammation (Inflammations) 12/2019 - 03/2005
6	Hyperlipidemias (Hyperlipidemia) 01/2013 - 09/2007
4	Obesity 09/2021 - 05/2009
3	Dyslipidemias (Dyslipidemia) 01/2020 - 09/2007
3	Carotid Artery Injuries 01/2019 - 06/2012
3	Myocardial Infarction 03/2016 - 02/2009
3	Malaria 01/2007 - 01/2003
2	Breast Neoplasms (Breast Cancer) 01/2021 - 04/2017
2	Infections 12/2019 - 12/2016
2	Platelet Glycoprotein IV Deficiency 01/2019 - 01/2016
2	Diabetes Mellitus 01/2019 - 12/2014
2	Atherosclerotic Plaque (Atheroma) 08/2013 - 08/2012
2	Vascular System Injuries 01/2013 - 05/2008
1	Hypertension (High Blood Pressure) 09/2021
1	COVID-19 09/2021
1	Hypertriglyceridemia 09/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2020
1	Pneumonia (Pneumonitis) 12/2019
1	Lung Injury 12/2019
1	Hyperplasia 01/2019
1	Vascular Diseases (Vascular Disease) 01/2019
1	Cerebral Infarction 01/2017
1	Stroke (Strokes) 03/2016
1	Carcinoma (Carcinomatosis) 01/2016
1	Wounds and Injuries (Trauma) 02/2015

Drug/Important Bio-Agent (IBA)

14	Scavenger Receptors (Scavenger Receptor)IBA 01/2020 - 10/2002
11	Proteins (Proteins, Gene)FDA Link 01/2020 - 11/2006
11	LipidsIBA 01/2020 - 09/2007
10	oxidized low density lipoproteinIBA 01/2020 - 10/2002
9	Apolipoproteins E (ApoE)IBA 01/2019 - 12/2004
8	Oxidants (Oxidizing Agents)IBA 01/2019 - 09/2007
7	LigandsIBA 01/2013 - 01/2007
4	Pharmaceutical PreparationsIBA 01/2021 - 01/2003
3	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020 - 10/2002
3	Fatty Acids (Saturated Fatty Acids)IBA 12/2019 - 01/2007
3	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 10/2011 - 03/2011
2	GlucocorticoidsIBA 09/2021 - 10/2015
2	src-Family KinasesIBA 01/2020 - 01/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 03/2005
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2020 - 01/2017
2	Membrane Proteins (Integral Membrane Proteins)IBA 01/2019 - 07/2011
2	Mitogen-Activated Protein Kinase 7IBA 11/2018 - 01/2017
2	Ephrin-B2 (Ephrin B2)IBA 04/2017 - 01/2016
2	Protein Kinases (Protein Kinase)IBA 04/2017 - 01/2017
2	Adenosine Triphosphatases (ATPase)IBA 09/2015 - 01/2013
2	ferric chlorideIBA 12/2014 - 01/2013
2	CalciumIBA 05/2014 - 10/2011
2	Insulin (Novolin)FDA Link 08/2012 - 02/2011
2	Peptides (Polypeptides)IBA 03/2012 - 01/2007
2	ThrombospondinsIBA 06/2011 - 01/2007
1	VimentinIBA 01/2022
1	Triglycerides (Triacylglycerol)IBA 09/2021
1	Metformin (Glucophage)FDA LinkGeneric 01/2021
1	AMP-Activated Protein KinasesIBA 01/2021
1	NADH oxidaseIBA 01/2021
1	Indicators and Reagents (Reagents)IBA 01/2020
1	HDL CholesterolIBA 01/2020
1	HDL LipoproteinsIBA 01/2020
1	Cysteine (L-Cysteine)FDA Link 01/2020
1	Apyrase (ATP Diphosphatase)IBA 12/2019
1	Virulence Factors (Pathogenicity Factors)IBA 12/2019
1	Type III Secretion SystemsIBA 12/2019
1	Type II Secretion SystemsIBA 12/2019
1	Thrombopoietin ReceptorsIBA 12/2019
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 12/2019
1	Hemostatics (Antihemorrhagics)IBA 01/2019
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2019
1	CalponinsIBA 01/2019
1	Contractile ProteinsIBA 01/2019
1	CollagenIBA 01/2019
1	Cyclin AIBA 01/2019
1	Collagen Type I (Type I Collagen)IBA 01/2019
1	FibrinIBA 11/2018
1	lysophosphatidic acidIBA 04/2017
1	Messenger RNA (mRNA)IBA 04/2017
1	Estrogen ReceptorsIBA 04/2017
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 04/2017
1	Cardiac GlycosidesIBA 01/2017
1	Ouabain (G Strophanthin)IBA 01/2017
1	plasma protein Z (protein Z)IBA 01/2017
1	AnionsIBA 01/2017
1	Superoxides (Superoxide)IBA 01/2017
1	Vitamin A (Retinol)FDA LinkGeneric 01/2017
1	ApolipoproteinsIBA 01/2017
1	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2017
1	carbapenemaseIBA 12/2016
1	LipopolysaccharidesIBA 12/2016
1	trimethyloxamine (trimethylamine N-oxide)IBA 03/2016
1	Choline (Choline Chloride)IBA 03/2016
1	Interleukin-6 (Interleukin 6)IBA 02/2015
1	Rosiglitazone (Avandia)FDA Link 02/2015
1	Acrolein (Aqualin)IBA 01/2015
1	CholesterolIBA 01/2015

Therapy/Procedure

2	Therapeutics 06/2008 - 01/2007
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2017
1	Intraperitoneal Injections 01/2017
1	Transplantation 03/2016